PGS, is a specialised reproductive technology that involves screening embryos for chromosomal abnormalities before they are implanted during In Vitro Fertilisation (IVF). This helps identify embryos with the best genetic makeup, increasing the chances of a successful pregnancy. Genea uses GeneSure to screen your embryos.

During your IVF cycle, a scientist will select an embryo for transfer based on its appearance — but a significant proportion of embryos that look normal under the microscope actually have chromosomal issues. Usually an embryo with a chromosomal abnormality will either not implant or miscarry, but sometimes you can fall pregnant with a child that has, for example, Down syndrome.

Some couples opt to try and avoid this, by having PGS. This reduces the risk of miscarriage, excludes any embryos with chromosomal errors, and allows us to better select the embryo most likely to implant. It may also mean that less embryo transfers are required to achieve a healthy baby.

PGS is typically recommended for couples with a history of recurrent miscarriage, advanced maternal age, or a known risk of carrying a genetic disorder. It ensures the selection of healthy embryos, reducing the likelihood of miscarriage and the birth of a child with genetic abnormalities.

- Patients who have multiple embryo transfers (>4-5) without success
- If you have had multiple miscarriages
- If you wish to avoid at all costs a termination of a Down syndrome pregnancy
- If you would prefer to have less embryos in storage
- Older patients (>37) who are more at risk of embryos with errors

PGS involves the biopsy of one or more cells from the embryo at the blastocyst stage (at day five or six of development). The embryos are then frozen & the cells tested. We screen for chromosomal abnormalities using the GeneSure technique. Single gene disorders such as cystic fibrosis can also be screened for if you are known to be at risk.

While PGS significantly improves the odds of selecting healthy embryos, it cannot guarantee a successful pregnancy or the birth of a healthy baby. Other factors, such as age, general health, age, embryo quality and uterine factors also play essential roles in achieving a successful pregnancy.

PGS is generally considered safe, but it does involve a minor risk of damaging the embryo during the biopsy process. However, advancements in technology have reduced these risks significantly. The benefits of selecting healthy embryos often outweigh the minimal risks involved.

It costs NPr per embryo for testing in addition to the cost of your IVF cycle. This is capped if you have 5 or more embryos for testing. Most people would have 1 to 3 blastocysts suitable for testing. If you have a genetic disorder (for example spinal muscular atrophy- SMA) the testing will also require a genetic workup & the costs will be reduced by a Medicare rebate.